Sanja Vickovic

SciLifeLab Fellow, Uppsala University

sanja.vickovic@scilifelab.uu.se

Keywords

aging, cancer biology, host-microbiome, Inflammation, neurodegeneration, technology development

Key publications

1. Vickovic S*, Eraslan G, Salmén F, Klughammer J, Stenbeck L, Schapiro D, Äijö T, Bonneau R, Bergenstråhle L, Navarro JF, Gould J, Griffin GK, Borg Å, Ronaghi M, Frisén J, Lundeberg J, Regev A, Ståhl PL. High-definition spatial transcriptomics arrays for in situ tissue profiling. Nat. Methods. 16: 987-990 (2019), doi: https://doi.org/10.1038/s41592-019-0548-y, number of citations: 558
*Corresponding author

2. Maniatis S*, Äijö T*, Vickovic S*, Braine C, Kang K, Mollbrink A, Fagegaltier D, Andrusivová Ž, Saarenpää S, Saiz-Castro G, Cuevas M, Watters A, Lundeberg J, Bonneau R, Phatnani H. Spatiotemporal Dynamics of Molecular Pathology in Amyotrophic Lateral Sclerosis, Science. 364, 89-93 (2019), doi: https://doi.org/10.1126/science.aav9776
*Equal contribution

3. Vickovic S*, Lötstedt B*, Klughammer J, Mages S, Segerstolpe A, Rozenblatt-Rosen O, Regev A. SM-Omics is an automated platform for high-throughput spatial multi-omics. Nat. Commun. 13, 795 (2022) doi: https://doi.org/10.1038/s41467-022-28445-y
*Equal contribution

4. Vickovic S*, Schapiro D, Carlberg K, Lötstedt B, Larsson L, Korotkova M, Hensvold SH, Catrina AI, Sorger PK, Malmström V, Regev A, Ståhl PL. Three-dimensional spatial transcriptomics uncovers cell type dynamics in the human rheumatoid arthritis synovium, Nat. Commun. Bio. 5: 129 (2021), doi: https://doi.org/10.1038/s42003-022-03050-3
*Corresponding author

5. Baker E, Schapiro D*, Dumitrascu B, Vickovic S*, Regev A*. In silico tissue generation and power analysis for spatial omics. Nature Methods (2023), doi: https://doi.org/10.1038/s41592-023-01766-6,
*Corresponding author

6. Vickovic S, Ståhl PL, Salmén F, Giatrellis S, Westholm JO, Mollbrink A, Navarro JF, Custodio J, Bienko M, Sutton LA, Rosenquist R, Frisén J, Lundeberg J. Massive and parallel expression profiling using microarrayed single-cell sequencing. Nat. Commun. 7, 13182 (2016), doi: https://doi.org/10.1038/ncomms13182

21. Lötstedt B, Strazar M, Xavier RJ, Regev A, Vickovic S*. Spatial host-microbiome sequencing. bioRxiv (2022). doi: https://doi.org/10.1101/2022.07.18.500470, number of citations: 1
*Corresponding author

SciLifeLab / Contact / Sanja Vickovic

The Vicković Lab is focused on developing novel “digital pathology” tools to track disease progression with the aim of identifying translatable drug and therapeutic targets in human tissue cohorts. The team leverages technologies including spatial transcriptomics, single-cell sequencing, and machine learning. The team studies why inflammation in the bowel increases the risk of cancer and what happens to our gut during aging.