Peter Nilsson
Professor in Proteomics
Division of Affinity Proteomics
Department of Protein Science, KTH
Platform Scientific Director: Clinical Proteomics and Immunology
Research interests
Neuroproteomics, Autoimmunity profiling, Infectious diseases & Multi-disease serology
The research in the group is devoted to highly multiplex protein and antibody profiling in body fluids based on various aspects of affinity proteomics. This is mainly enabled through the development and utilization of different types of protein array formats using proteins and antibodies from the Human Protein Atlas.
The main focus within neuroproteomics is on multiplex protein and autoantibody profiling in plasma, serum and CSF within amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), Alzheimer’s disease, Parkinson’s diseases and psychiatric disorders. (PI Anna Månberg)
The autoimmunity disorders mainly being explored and characterized for their autoantibody repertoires are currently vasculitis, systemic sclerosis, myositis, sarcoidosis and fibrosis. (PI Elisa Pin)
During the early phase of the pandemic, we rapidly developed a highly specific and sensitive high-throughput multiplex bead-based serological assay for SARS-CoV-2 that has been used to analyse over 250,000 samples. We are now extending the assay to provide a platform for multi-disease serology including a wide range of antigens representing various respiratory and infectious diseases.
Combinations of highly multiplex protein, autoantibody and serology profiling in association to studies of infectious diseases and vaccinations are now being emphasized within several international collaborations, with a focus on mosquito spread diseases, currently mainly affecting tropical and subtropical areas, such as dengue, zika and chikungunya, and also malaria.
Group members
Infectious diseases
Sofia Bergström, researcher
Priscilla Silva, postdoc
Anna Gardell, PhD-student
Lovisa Skoglund, research engineer
Tilde Nordlander, master student, KTH
Neuroproteomics
PI Anna Månberg, researcher, docent
Inci Aksoylu, postdoc
Jennie Olofsson, research engineer
Sofia Bergström, researcher
Rebecca Randleff, master student, KTH
Kristian Pelligra, master student, KTH
Autoimmunity profiling
PI Elisa Pin, researcher
Charlotta Preger, postdoc
Maria Aspenberg, research engineer
Ceke Hellström, research engineer
Eni Andersson, research engineer
Metta Berenpas, master student, Radboud University
Alumni at Div Affinity Proteomics