SweGen genomic data for 1,000 individuals now available through FEGA Sweden

The SciLifeLab bioinformatics platform, NBIS, is pleased to announce that four datasets from the SweGen study have been added to the FEGA Sweden repository. These datasets include whole-genome sequencing (WGS) data for 1,000 individuals in compressed format (CRAM), with variant data provided in Variant Call Format (VCF). This addition provides an invaluable resource for studying genetic variation in the Swedish population.

The datasets can be found through the European Genome-phenome Archive (EGA) website. Researchers can submit access requests for the deposited data, which will be handled by Research Data Support at Uppsala University (UU).

SweGen is a national initiative aimed at mapping genetic variation in Sweden, conducted by the NGI platform at SciLifeLab. Adding these datasets to FEGA Sweden, hosted by NBIS, makes the SweGen data more easily discoverable and accessible. Significantly enhancing the availability of population-specific genomic data. The inclusion of VCF files makes it more convenient for researchers to explore the genetic variation in the WGS data. Advancing research in population genetics, genomics, and precision medicine.

“This work forms an important component in making data sequenced at NGI available to a broader audience through NBIS, and leverage the SciLifeLab resources. An effort that also continues in the European population genomic project “Genome of Europe,” says Anna Hagwall, Head of human data at NBIS. 

Contracts for handling data in FEGA Sweden already exist for all major universities in Sweden. Collaboration is in progress to create joint processes and define roles at these data submitter sites. Now that the processes for data from UU are designed and implemented, it will be easier and quicker for other researchers at UU to deposit their data.

Remains available from the SweFreq resource

Aggregated variant frequency information for the SweGen cohort will continue to be available from the SweFreq resource, also hosted by NBIS. SweFreq serves as a tool for both research and clinical genetics by offering insight into the allele frequencies within the Swedish population.