Clinical Genomics Lund

Clinical Genomics Lund was established in 2016 as a joint strategic initiative between the Medical Faculty at Lund University and the Division of Laboratory Medicine, Medical Services, Region Skåne. The unit encompasses two centers, Center for Translational Genomics (CTG) and Center for Molecular Diagnostics (CMD) that are fully aligned and operate in tight synergy, but with separate responsible bodies and budgets (Lund University and Region Skåne, respectively). Clinical Genomics Lund aims to provide state-of-the-art next generation sequencing (NGS)-based services to strong and high-profile translational research projects and to implement new NGS-based tests for clinical diagnostics within the healthcare system aiming at broader national coverage and consensus.

Applications

We provide expertise, method development and end-to-end service to translational research and precision diagnostics for the development of tomorrow’s diagnostics. Our current disease focus areas are:

• Cancers (including solid tumors and hematological malignancies)
• Rare inherited disease
• Microbial diseases and surveillance

Services

Our national services within NGS and other molecular technologies include development of methods for clinical implementation or translational research with strong clinical utility. These include, but are not restricted to:

• Consultation (Project design)
• QC of samples for various analyses (Sequencing data, Genomic DNA/RNA)
• Sequencing:
  • DNA sequencing (WGS, WES, Panels, microbial genomes, ctDNA)
  • RNA sequencing (total RNA, mRNA)
  • Single-cell transcriptomics and epigenomics (GEX, Flex, CITE-Seq, ATAC, Multiome)
• Bioinformatics (Software support, Bioinformatic analysis)

Equipment

• Various automatic robotic systems (Tecan, Hamilton, Myra Liquid Handler)
• Various systems for QC, quantification and fragment analyses (Agilent TapeStation 4200, Thermo Fisher QubitFlex and QuantStudio)
• Sequencing platforms
  • Illumina (NextSeq 2000, NovaSeq 6000, NovaSeq X Plus)
  • 10x Genomics (Chromium X, CytAssist)
  • Cell isolation (Scienion CellenOne)
  • Other single-cell equipment (Cellaca)

Accessing the Local Unit

For more information about our services, please visit our websites:

Clinical Genomics platform

If you do not find the service or technology you require, contact us at info-clinical-genomics@scilifelab.se