How protein degraders work: Molecular mechanism and drug design
Alessio Ciulli Professor of Chemical Structural Biology Founder and Director, Centre for Targeted Protein Degradation School of Life Sciences, University of Dundee Abstract Protein degraders (also known as PROTACs and molecular glues) are a new class of small molecule tools and drugs that trigger the rapid depletion of a target protein inside the cell. Degraders work […]