Researcher Biologics Drug Discovery at the DDD platform
School of Engineering Sciences in Chemistry, Biotechnology and Health at KTH
Job description
The Drug Discovery & Development platform at the Science for Life Laboratory (SciLifeLab DDD) is a national infrastructure for academic drug development with the task of translating academic discoveries into drug candidates for further commercial development. The business, which has existed for almost ten years, has, among other things, contributed to >10 new companies and four clinical drug candidates. The platform includes around 40 employees at six Swedish universities who all support collaborative projects with external academic project owners.
The DDD unit “Therapeutic Protein Engineering” (TPE) is attached to KTH and located at SciLifeLab DDD, Solna. The unit’s main responsibility is to deliver well-characterized antibodies, antigens, and target proteins to the projects, as well as be technically responsible for the selection-based projects.
Your tasks will be to develop expression and purification protocols for challenging target proteins in our drug discovery projects, as well as to analyze and characterize protein properties such as functionality and conformation using various biochemical and biophysical techniques. Your role will be both lab-based and coordinative.
What we offer
- A position at a leading technical university that generates knowledge and skills for a sustainable future.
- Engaged and ambitious colleagues along with a creative, international and dynamic working environment
- Work in Stockholm , in close proximity to nature
- Help to relocate and be settled in Sweden and at KTH
Read more about what it is like to work at KTH.
Qualifications
Requirements
- PhD or equivalent in biotechnology, biochemistry or molecular biology
- Thorough experience in cloning, overexpression and purification of proteins in bacteria, insect cells and/or mammalian cells
- Protein purification using ÄKTA or comparable systems
- Thorough knowledge of standard protein analysis methods
- Experience with biophysical protein analysis methods, e.g. ITC, DLS and DSF
Preferred qualifications
- Experience from biotech/pharmaceutical industry or relevant academic research environment
- Experience with structural biology, especially cryo-EM
- Experience with SPR
- Experience with protein engineering
- Excellent writing and communication skills
- Project management and coordination
- Knowledge of diversity and equal opportunity issues, with specific focus on gender equality
- Good collaborative abilities and a high level of independence
Great emphasis will be placed on personal skills.
Trade union representatives
Contact information to trade union representatives.
To apply for the position
Log into KTH’s recruitment system in order to apply for this position. You are responsible to ensure that your application is complete according to the instructions in the ad. Your complete application must be received at KTH no later than the last day of application.
The application must contain:
- CV including relevant professional experience and knowledge.
- Copy of diplomas and grades from your previous university studies. Translations into English or Swedish if the original documents are not issued in either of these languages.
- Personal letter (1 page)
Your complete application must be received by KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time).
About the employment
The employment is valid until further notice (permanent post) according to agreement.
The employment begins with a six-month probationary period.
Other information
Striving towards gender equality, diversity and equal conditions is both a question of quality for KTH and a given part of our values.
For information about processing of personal data in the recruitment process.
According to The Protective Security Act (2018-585), the candidate must undergo and pass security vetting if the position is placed in a security class. Information regarding whether the position is subject to such a classification will be provided during the recruitment process.
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Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence
About KTH
KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy. Read more here