Peter Nilsson
Professor in Proteomics
Division of Affinity Proteomics
Department of Protein Science, KTH
Platform Scientific Director: Clinical Proteomics and Immunology
We are recruiting a PhD-student in affinity proteomics with a focus on protein and antibody profiling in infectious diseases
Research interests
Neuroproteomics, Autoimmunity profiling, Infectious diseases & Multi-disease serology
The research in the group is devoted to highly multiplex protein and antibody profiling in body fluids based on various aspects of affinity proteomics. This is mainly enabled through the development and utilization of different types of protein array formats using proteins and antibodies from the Human Protein Atlas.
The main focus within neuroproteomics is on multiplex protein and autoantibody profiling in plasma, serum and CSF within amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), Alzheimer’s disease, Parkinson’s diseases and psychiatric disorders. (PI Anna Månberg)
The autoimmunity disorders mainly being explored and characterized for their autoantibody repertoires are currently vasculitis, systemic sclerosis, myositis, sarcoidosis and fibrosis. (PI Elisa Pin)
During the early phase of the pandemic, we rapidly developed a highly specific and sensitive high-throughput multiplex bead-based serological assay for SARS-CoV-2 that has been used to analyse over 250,000 samples. We are now extending the assay to provide a platform for multi-disease serology including a wide range of antigens representing various respiratory and infectious diseases.
Combinations of highly multiplex protein, autoantibody and serology profiling in association to studies of infectious diseases and vaccinations are now being emphasized within several international collaborations, with a focus on mosquito spread diseases, currently mainly affecting tropical and subtropical areas, such as dengue, zika and chikungunya, and also malaria.
Group members
- Anna Månberg, researcher
- August Jernbom Falk, researcher
- Ceke Hellström, research engineer
- Charlotta Preger, postdoc
- Edvin Ljungquist, research engineer
- Elisa Pin, researcher
- Eni Andersson, research engineer
- Inci Aksoylo, postdoc
- Jennie Olofsson, research engineer
- Lovisa Skoglund, research engineer
- Maria Aspenberg, research engineer
- Priscilla Silva, postdoc
- Ronald Sjöberg, head of unit
- Sára Mravinacová, researcher
- Sofia Bergström, researcher